I have a similar problem, (difference: 18 seats) I had already checked the ownership and permissions. Our computers are in a lab. If I create a local account on the computer VectorWorks works. If the students log in under Active Directory (which is a state accountability requirement) they receive the generic icon. If they click on that icon, they get an error message: You cannot open ?VectorWorks? because it is not supported on this architecture. Thanks for any help you can give. If you need additional information, please let me know.