So I spent an additional 2-3 hours today on trying every possible permission setup I could, taking control of the program, uninstalling/reinstalling, trying a different file to install from, copying the exact same permissions shown on my AutoCAD, etc. and to no avail. Unless you (Jim) or someone else can help with this, I'm going to have to walk away from Vectorworks. As much as I have enjoyed working with the program so far, it's unfortunately useless to me without having the ability to save. I've dumped hours into trying to fix this issue because I really wanted to use Vectorworks, but I'm going to need to give it up soon and start focusing on something else. Incredibly disappointed (not to mention frustrated).