Studio has more memory and far more cooling. So something like renders that run for and extended period of time (more than say 10 minutes) may cause a Mini to throttle due to the thermal envelope where the Studio can probably run flat out continuously.   A Mini with 32 (or even 16) GB is probably sufficient for 90% of the Vectorworks users. The people you see on this board (you @line-weight, @Christiaan, @Mark Aceto, @jeff prince, etc.) are high end power users and are going to want mo