One way to help reduce clutter on your screen is to learn the keyboard commands associated with each palette item. Since the commands work even if the palette is closed, you can use them instead of taking up valuable screen real estate. To find and change these command keys, you can use the Workspace Editor.
Some users even like to make a super palette with all the common tools and keys assigned. Then, they can just use a few very small palettes with the more obscure, or task-oriented tools.
Edited by JimW