You know more than you may think! The PhysX selection on it's own usually wont do it, but often setting both that AND under Manage 3D Settings, set the Global preferred graphics processor to the eGPU. Sometimes if I only set the preferred GPU it didnt work, but setting both did the trick.  After we are out of NDA on the eGPU housing model we are currently testing, ill post a kbase article with what I've learned.
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