Hi Brent,
There are many ways to use layers and classes in VectorWorks. The way I use layers are the same as using different drawing sheets or individual paper sheets in hand drawing each with a different scale as needed. Example A-1, A-2, A-3, etc. would all be on different layers.
I use classes the same way as an AutoCAD user would use layers in that program. Classes are used to group similar components such as dimensions, text, walls, etc so that the user can turn these "thing" on and off within each layer.
There are other ways to use these features but this is how our office uses classes and layers.
Hope this helps.
Jeff