I believe I figured it out, however looking for confirmation.
The "Device Builder" creates the spacing based on the grid/snap settings in combination with the "ConnectCAD Settings" connector spacing options.
If you change the grid/snap spacing mid project and then use Device Builder, the spacing of the new symbols will be based on the current grid/snap settings.
It may be helpful to disconnect the association between the grid/snap and the ConnectCAD device layout spacing so this doesn't happen in the future.
If this is not supposed to function this way, or if I solved my problem via the wrong method, please let me know.