I use Vectorworks on two machines--a desktop and a laptop. Several months ago, I moved my user folder to a Dropbox folder. This way, when I update workspaces and such on one machine, it would transfer over to the other machine the next time I started it up.
The downside has been that I regularly have to "Activate" again, and now for the third time, I have had to call in because I have exceeded activations. I'm only using it on two machines so I don't know what the fix is..