Lighting and texture creation will be key to whatever you do and wherever you render. If you have some familiarity with renderworks and clearly have the program, part there.
I might suggest rather than try to render an entire project, start with simple forms, build textures, render those, see what works, then you can also ask specific question her "How do I make the XX better?"
Same with lighting, the fewer the lights, the better for speed no matter the application. Frankly, a lot can be done with the proper lights properly placed. Avoid the point light.
Look at Renderworks Styles, with and without HDRI illumination, you do not need to start with high quality or FQR. go for speed, test and repeat.
I;'m a Mac user, so I can't speak to mum ion, but Twinmotion requires a lot of computing power. It deliver magnificent work.Moving back and forth between VWX and C4D can be a bit tedious in the early design stages, but you can also use C4D to create textures for VWX.